OUR TEAM

AmPharmStatistics.com is comprised of an elite team of experts in the fields of biostatistics and statistical methods. We are here to consult with you, answer any questions you may have and satisfy all of your needs.

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Robert B. MacArthur

PharmD, MS CEO

Robert B. MacArthur received his PharmD from St. John’s University and MS in Biostatics from Columbia University in New York. From 1988 to 1994 he directed a 60-bed Phase-I unit for LAB Incorporated, and also worked for Sandoz Pharmaceuticals in Drug Safety and Product Labeling.

From 1994 to 2010, he was Director of the Research Pharmacy at Columbia University, directing drug preparation, packaging, dispensing, and distribution for in-hospital trials, ambulatory clinic studies, and multi-centered international trials. From 2010 to 2013 he directed

orphan drug development projects at Orphan Drug Services, Inc. He is currently Vice President of Clinical Development at Pharmaceutics International Incorporated, in Hunt Valley, MD USA, and a lecturer in Drug Development and Regulatory Affairs.

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Bruce Levin, Ph.D.

Design Consultant

Bruce Levin, Ph.D., is Professor and Past Chair of the Department of Biostatistics at Columbia University’s Mailman School of Public Health. He has a long-standing interest in statistical methodology for clinical trials, public health, and the law. Using sequential statistical methods, he has published on innovative trial designs, e.g., designs that minimize ethical costs, designs that emphasize the selection paradigm rather than the significance testing paradigm, and novel designs such as the comparative selection trial which combines features of both paradigms. For example, in May of 2009 he gave a short course to the FDA/CDER biostatistics group entitled, “Selection Methods in Clinical Trials.”

Dr. Levin enjoys putting theory into practice and has served as the senior statistical consultant on several multicenter randomized clinical trials in the field of stroke neurology and cardiology, including the WARCEF trial funded by NINDS (Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction), the WARSS trial (Warfarin versus Aspirin in Recurrent Stroke Study), the GAIN Americas trial, and the CABG Patch trial. He has also served for the last 20 years as the Director of the Statistics, Epidemiology, and Data Management (SED) Core of the HIV Center for Clinical and Behavioral Studies.

Dr. Levin is a Fellow of the American Statistical Association. He co-authored the 3rd edition of Statistical Methods for Rates and Proportions with Myunghee Cho Paik and the late Joseph L. Fleiss. Dr. Levin served for ten years as Consulting Statistical Editor for the American Journal of Public Health. He has also served as an expert statistical witness in many court cases, and is co-author with Michael O. Finkelstein of Statistics for Lawyers, now in its second edition.

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Arman Altincatal, Ph.D.

Senior Programmer and Statistician

Arman Altincatal, MS, is a pharmaceutical industry based senior statistician. Mr. Altincatal specializes in statistical methods for clinical trials and observational (large epidemiological cohort) data analyses. He is familiar with a broad range of statistical methods, such as mixed models, repeated measures logistic regression, and survival analysis with time-dependent predictors.

Mr. Altincatal has worked in various disease areas, including cardiovascular, Alzheimer’s, depression, anxiety disorders, chronic liver disease, and oncology. His areas of interests are parametric and non-parametric survival analysis techniques involving time-dependent variables, mixed models for longitudinal and correlated data and analysis of non-linear data.

Mr. Altincatal received his undergraduate degree in Mechanical Engineering/Aerospace Option from Rochester Institute of Technology and obtained his Master of Science degree in Biostatistics from Columbia University Mailman School of Public Health.

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Seamus (John L P) Thompson, Ph.D.

Director of the Statistical Analysis Center (SAC)

Seamus (John L P) Thompson PhD is a Professor of Clinical Biostatistics and Clinical Neurology at Columbia University and Director of the Statistical Analysis Center (SAC) in the Department of Biostatistics. He is an applied statistician specializing in innovative collaborations in prevalent and rare neurological and other disorders. He has, with colleagues, developed an approach to clinical trials and which combines collaboration with eminent clinical investigators, innovative statistical designs, and advanced, customized, flexible, user-friendly data management systems. Seamus has served as Principal Investigator for Statistics and Data Management in major NIH multicenter trials (WARCEF, TNK, QALS, and has participated in industry trials (GAIN, Abciximab, ReoPro) and other collaborations, such as the NIH-funded North American Mitochondrial Research Consortium (NAMDC). He has also served on many trial Data and Safety Monitoring Boards (DSMBs).

He is interested in finding new ways to shorten the development path for new therapies for patients with rare and ultra-rare diseases, and in 2010 presented a formal proposal to the FDA in a public hearing on how the statistical aspects of the approval process for rare diseases might be improved.